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Updated: Jan 16, 2026

A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
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Multilevel Optimization of 3-Ketosteroid-9α-Hydroxylase for Enhanced 9α-Hydroxy-4-androstene-3,17-dione Production

Jing Tao1, Ting Zhang1, Kun Jiang1

  • 1College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.

ACS Synthetic Biology
|October 2, 2025
PubMed
Abstract

Keywords:
3-ketosteroid-9α-hydroxylase9α-hydroxy-4-androstene-3,17-dioneNADH regenerationcomputational designmicrobial cell factory

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