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Labia majora lifting technique with polydioxanone threads
Savas O Aglamis1, Selver K Akkaya2, Elif O Sahin3
1Department of Obstetrics and Gynecology, Dr. Ozgur Aglamis Private Clinic, 34381, Sisli, Istanbul, Turkey.
Sexual Medicine
|October 2, 2025
Summary
Polydioxanone (PDO) thread lifts significantly improved labia majora hypotrophy, enhancing self-image and sexual function. This minimally invasive rejuvenation offers a safe and effective alternative to traditional surgical methods.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Plastic Surgery
Background:
- Polydioxanone (PDO) threads are synthetic, absorbable sutures utilized for cosmetic rejuvenation and lifting procedures.
- Labia majora hypotrophy is a condition often addressed through surgery, fat grafting, or hyaluronic acid fillers.
Purpose of the Study:
- To evaluate the efficacy and safety of using polydioxanone (PDO) threads for rejuvenation and enlargement in patients with labia majora hypotrophy.
- To assess the impact of PDO thread suspension on female genital self-image.
Main Methods:
- A prospective study involving 21 patients diagnosed with labia majora hypotrophy.
- Application of a PDO thread suspension technique using 50 mm screw threads (30G-38mm needle) with 10 threads per side.
- Preoperative and postoperative assessment using the Female Genital Self-Image Scale (FGSIS).
Main Results:
- The overall FGSIS total score showed a statistically significant increase post-intervention.
- All individual parameters within the FGSIS demonstrated significant improvement from preoperative to postoperative scores.
- The PDO thread procedure exhibited a favorable safety profile in this patient cohort.
Conclusions:
- PDO thread suspension is a minimally invasive and effective method for labia majora lifting and rejuvenation.
- This technique offers comparable results to traditional methods with potential advantages in invasiveness.
- The procedure positively impacts patients' self-confidence and sexual function, making it a preferable alternative to surgery.

