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Hepatitis E Virus Infection in a Liver Transplant Recipient Presenting With Late-Onset Acute Rejection and Treated
Daffolyn Rachael Fels Elliott1, Jwan Alallaf1, Devin Shrock1
1Department of Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, Kansas, USA.
Case Reports in Transplantation
|October 2, 2025
Summary
Hepatitis E virus (HEV) can cause liver problems in transplant recipients, often without clear symptoms. Early HEV testing is crucial for transplant patients with unexplained liver enzyme increases, especially after rejection treatment.
Area of Science:
- Hepatology
- Transplant Medicine
- Virology
Background:
- Hepatitis E virus (HEV) is an emerging cause of allograft hepatitis in transplant recipients.
- Persistent HEV infection can be asymptomatic, with subtle liver biopsy findings, necessitating high clinical suspicion for diagnosis.
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