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Updated: Jan 16, 2026
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A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
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PROTOCOL: New-Onset Diabetes Mellitus Post COVID-19 Infection: A Protocol for Systematic Review and Meta-Analysis: A
Emma Cocking1, Joseph Daher1, Majid Alabbood1,2
1School of Medicine The University of Notre Dame Australia Sydney New South Wales Australia.
Campbell Systematic Reviews
|October 2, 2025
Summary
This review examines new-onset diabetes mellitus after COVID-19 infection. Evidence suggests a link, prompting further investigation into this critical public health concern.
Area of Science:
- Endocrinology
- Infectious Diseases
- Public Health
Background:
- Emerging evidence links coronavirus disease 2019 (COVID-19) to new-onset diabetes mellitus.
- This association is observed in patients without a prior history of diabetes.
Purpose of the Study:
- To determine the incidence of new-onset diabetes mellitus in COVID-19 patients versus controls.
- To analyze rates of diabetic ketoacidosis, hyperglycemia, mortality, and ICU admission.
- To investigate subgroup analyses including corticosteroid use and hospitalization.
Main Methods:
- Systematic review and meta-analysis following PRISMA-P guidelines.
- Inclusion of published cohort studies from December 2019 onwards.
- Data extraction and risk of bias assessment by independent reviewers.
Main Results:
- The review will compare the relative risk of new-onset diabetes mellitus post-COVID-19.
- Subgroup analyses will explore factors influencing diabetes incidence.
- Long-term incidence (6-12 months post-infection) will be reported.
Conclusions:
- Findings will elucidate the COVID-19 and diabetes mellitus relationship.
- Results will inform clinical management for at-risk populations.
- Understanding this link is crucial for public health strategies.
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