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Predicting Repetitive Negative Thinking in Daily Life: Insights From Brain-Based Graph-Theoretical Predictive

Martino Schettino1, Rotem Dan2, Chiara Parrillo3

  • 1Center for Depression, Anxiety, and Stress Research, McLean Hospital, Belmont, Massachusetts; Department of Psychology, Sapienza University of Rome, Rome, Italy; IRCCS Institute of Neurological Science of Bologna, Bologna, Italy.

Biological Psychiatry. Cognitive Neuroscience and Neuroimaging
|October 2, 2025
PubMed
Summary

Brain network abnormalities predict daily repetitive negative thinking (RNT). Graph-theoretical modeling identified specific network features linked to RNT severity and intrusiveness, offering insights into RNT's emergence.

Keywords:
Ecological momentary assessmentFunctional connectomeGraph theoryPredictive modelingRuminationfMRI

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