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Updated: Jan 16, 2026
MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
Published on: December 13, 2017
Postmortem Analysis 35 Months after Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor
Saachi Jhandi1, Lubdha Shah2, Henrik Odéen2
1Spencer Fox Eccles School of Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy offers sustained essential tremor (ET) relief. Long-term postmortem analysis reveals localized demyelination and tract disruption, confirming MRgFUS safety and precision.
Area of Science:
- Neurology
- Neurosurgery
- Medical Imaging
Background:
- Essential tremor (ET) is a common neurological disorder.
- Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is a novel non-invasive treatment for ET.
- Limited postmortem data exists on the long-term neuropathological effects of MRgFUS thalamotomy.
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