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Management of Retrograde Peri-Implantitis Using Guided Bone Regeneration.

Anthony L Neely1, Minkie Kim2, Joseph Samona2

  • 1Associate Professor, Department of Graduate Periodontics, Division of Graduate Education, University of Detroit Mercy School of Dentistry, Detroit, Michigan; Private Practice, Southfield, Michigan.

Compendium of Continuing Education in Dentistry (Jamesburg, N.J. : 1995)
|October 3, 2025
PubMed
Summary

Retrograde peri-implantitis (RPI) causes bone loss around dental implants. Guided bone regeneration (GBR) effectively treated RPI in two cases, showing bone fill and reduced probing depths.

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Area of Science:

  • Dentistry
  • Oral Surgery
  • Regenerative Medicine

Background:

  • Retrograde peri-implantitis (RPI) is a progressive bone loss condition at the periapex of dental implants.
  • While less common than marginal peri-implantitis, untreated RPI can result in dental implant loss.

Purpose of the Study:

  • To evaluate the efficacy of guided bone regeneration (GBR) for treating retrograde peri-implantitis (RPI).

Main Methods:

  • A clinical case series involving two patients with distinct RPI presentations.
  • Treatment involved guided bone regeneration (GBR) utilizing bone graft material and a collagen membrane.

Main Results:

  • Long-term follow-up demonstrated significant clinical and radiographic improvements.
  • Radiographic evidence showed substantial bone fill in the defects.
  • Probing depths around the treated implants were reduced.

Conclusions:

  • Guided bone regeneration (GBR) appears to be an effective treatment strategy for defects resulting from retrograde peri-implantitis (RPI).
  • GBR can lead to successful bone regeneration and improved clinical outcomes in RPI cases.