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Updated: Jan 16, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Enhancing randomized clinical trials with digital twins
Hossein Akbarialiabad1,2,3,4,5, Amirmohammad Pasdar6, Dédée F Murrell2,3
1University of Utah, Salt Lake City, UT, USA.
Abstract:
Digital twins (DTs) can transform randomized clinical trials by improving ethical standards, including safety, informed consent, equity, and data privacy. They also enhance trial efficiency by enabling early detection of adverse events and streamlined design. This paper explores the role of DTs in personalized medicine, from pre-clinical research to post-marketing, while addressing technological, legal, and ethical challenges in implementation.
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