Related Experiment Video
Updated: Jan 16, 2026
04:33
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
Published on: April 26, 2024
1.2K
Patient-Reported Outcome Measures to Determine Sleep Problems in Adults With Chronic Kidney Disease: A Systematic
Wan-Shan Chiang1, Louise Purtell1,2, Katina Corones-Watkins1
1School of Nursing and Midwifery, Griffith University, Brisbane, Queensland, Australia.
Journal of Renal Care
|October 4, 2025
Summary
Adults with chronic kidney disease (CKD) experience sleep problems. This review identified patient-reported outcome measures for assessing sleep quality in CKD, highlighting the need for broader validation.
Area of Science:
- Nephrology
- Sleep Medicine
- Psychometrics
Background:
- Chronic kidney disease (CKD) significantly impacts patient wellbeing, with sleep disturbances being a common and detrimental issue.
- Patient-reported outcome measures (PROMs) are crucial for evaluating sleep quality and symptom severity in individuals with CKD.
- Selecting appropriate PROMs requires understanding their characteristics and psychometric properties.
Purpose of the Study:
- To systematically review and identify optimal patient-reported outcome measures for assessing sleep quality and/or problems in adults with chronic kidney disease.
- To evaluate the characteristics and psychometric properties of available sleep assessment instruments for the CKD population.
Main Methods:
- A systematic review of the literature was conducted, searching major databases (CINAHL, MEDLINE, Embase, Cochrane Library, PsycINFO, JBI).
- Studies published between January 2010 and December 2023 were included.
- Methodological quality of the identified instruments was assessed using COSMIN-COMIT guidelines.
Main Results:
- Nineteen sleep assessment instruments were identified for use in the chronic kidney disease population.
- The Pittsburgh Sleep Quality Index (PSQI) was the most frequently used (73.8%) but is primarily validated in kidney transplant recipients.
- Other instruments like the Athens Insomnia Scale, Epworth Sleepiness Scale, STOP-BANG, and Berlin Questionnaire offer narrower assessments or are less practical for broad sleep evaluation in CKD.
Conclusions:
- There is a critical need to validate existing sleep instruments in non-transplant chronic kidney disease populations using rigorous psychometric testing.
- Clinicians and researchers should consider using multiple instruments to comprehensively assess both general sleep quality and specific sleep disorder symptoms in CKD patients.
- Further research is essential to refine and validate tools for accurate sleep assessment in the broader CKD population.
Related Concept Videos
01:28Chronic Kidney Disease III: Interprofessional Care
339
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
339
01:18Chronic Kidney Disease IV: Nursing Management
321
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
321
01:25Chronic Kidney Disease I: Introduction
560
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
560
01:24Chronic Kidney Disease II: Clinical Manifestations
552
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
552
01:28Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
189
Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area.
189
01:17Factors Affecting Renal Clearance: Renal Impairment
425
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
425