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Burden Estimation and Seasonality of Respiratory Syncytial Virus among Hospitalized Children in Kashmir, Northern

Bashir Ahmad Fomda1, Aamina Samreen2, Mushtaq Ahmad Bhat3

  • 1Professor and Head, Department of Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.

Indian Journal of Public Health
|October 4, 2025
PubMed

Insights

Respiratory syncytial virus (RSV) significantly impacts hospitalized children under five in Kashmir. This study highlights the high burden of RSV infections, particularly RSV A, during winter months in this region.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Respiratory syncytial virus (RSV) is a leading cause of severe respiratory illness in young children globally.
  • Limited epidemiological data exists for RSV in Kashmir, Northern India, hindering targeted public health interventions.

Purpose of the Study:

  • To determine the burden and seasonality of RSV infections in hospitalized children under 5 years old in Kashmir.
  • To identify the predominant RSV strains (A and B) circulating in the region.

Main Methods:

  • Nasopharyngeal samples were collected from hospitalized children (<5 years) with acute respiratory tract infections.
  • Multiplex RT-polymerase chain reaction was used to detect RSV A and B.
  • Demographic and seasonal data were analyzed to understand transmission patterns.

Main Results:

  • Overall RSV positivity was 31.8%, with RSV A at 30.3% and RSV B at 1.5%.
  • Infection rates were highest in infants (<1 year) at 41.8%, urban populations at 43.8%, and during winter at 46.77%.

Conclusions:

  • RSV poses a significant health burden on hospitalized children under five in Kashmir.
  • The findings underscore the need for increased awareness and potential interventions for RSV prevention and control in the region.
Abstract

Keywords:
Burden estimationchildrenmultiplex RT-polymerase chain reactionrespiratory syncytial virusrespiratory tract infections

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