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Published on: March 8, 2012
Human Papillomavirus Prevalence and Genotype Distribution in Dongguan, China
Minla Rao1,2, Jianjun Chen1,2, Wenbin Lai1,2
1Department of Laboratory Science, Binhaiwan Central Hospital of Dongguan, Dongguan City, Guangdong Province, China.
Introduction:
Cervical cancer is strongly associated with human papillomavirus (HPV) infection. In this retrospective study, we analyzed the data of individuals who were tested for HPV at Binhaiwan Central Hospital in Dongguan.
Methods:
We retrospectively analyzed the data of 73,149 participants who underwent HPV examination at Binhaiwan Central Hospital in Dongguan. All participants were tested for HPV genotypes. We subsequently analyzed the infection rate and evaluated the distribution of HPV using the Chi-square test.
Results:
The results suggest that the five most common HPV infection genotypes for men in the Dongguan area are different from those for women. The five most common high-risk HPV infections in women were the HPV52, 16, 58, 53, and 68 genotypes, whereas the five most common genotypes in men were HPV52, 16, 51, 58, and 39. The highest HPV infection positivity rate for female patients (31.68%) was in the 31-40 year age group, whereas the highest HPV infection positivity rate for male patients (40.47%) was in the 21-30 year age group.
Conclusions:
These findings provide a theoretical basis for epidemiological investigations, clinical prevention, and treatment of HPV infection and HPV vaccination in the region. The results could provide valuable information for healthcare professionals and policymakers to develop targeted prevention and screening strategies for reducing the burden of HPV-related diseases in this population.
