RHEOLOGICAL PARAMETERS OF CAROTID CIRCULATION IN METABOLIC SYNDROME WITH OR WITHOUT DIABETES MELLITUS

Area of Science:

• Cardiovascular Medicine
• Medical Imaging
• Rheology

Background:

• Metabolic syndrome (MetS) is a cluster of conditions that increase the risk of heart disease, stroke, and diabetes.
• Diabetes mellitus (DM) is a chronic condition that affects how your body turns food into energy.
• Carotid artery disease is a condition in which the carotid arteries become narrowed or blocked.

Purpose of the Study:

• To investigate the rheological parameters of carotid arteries in patients with metabolic syndrome (MetS) with and without diabetes mellitus (DM).
• To determine the frequency of abnormal rheological values in these patient groups.
• To assess the association between MetS, DM, and carotid artery disease.

Main Methods:

• The study included 90 subjects divided into two equal groups: MetS without DM and MetS with DM.
• Peak systolic velocity (PSV) was used as a reference for pathological rheological parameters.
• Carotid artery rheological parameters were analyzed using Doppler ultrasound.

Main Results:

• The MetS + DM group exhibited a higher incidence of pathological rheological parameters compared to the MetS-only group.
• Pathological PSV values were observed in the right internal carotid artery (ICA) in 12 patients within the MetS + DM group.
• Total flow obstruction in the left ICA and severe narrowing of the right ICA were noted in one patient with MetS + DM, indicating significant carotid artery disease.

Conclusions:

• The frequency of carotid rheological abnormalities is significantly higher in patients with both MetS and DM.
• Internal carotid arteries (ICA) were more susceptible to pathological changes.
• Screening rheological parameters in MetS patients is vital for preventing cerebrovascular disease.