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Responses in Posttherapy Recovery-Based Virtual Reality With Blood Flow Restriction in Older Women: A Randomized
Silas de Oliveira Damasceno1, Eduardo Pizzo Junior1, Allysiê Priscilla de Souza Cavina2
1Postgraduate Program in Movement Sciences, Universidade Estadual Paulista (FCT/UNESP), Presidente Prudente, SP, Brazil.
Journal of Aging and Physical Activity
|October 6, 2025
Summary
Combining blood flow restriction (BFR) with virtual reality-based therapy (VRT) did not disrupt autonomic, hemodynamic, or perceptual responses in older women post-exercise. This VRT-BFR intervention appears safe for this demographic.
Area of Science:
- Exercise Physiology
- Rehabilitation Science
- Gerontology
Background:
- Blood flow restriction (BFR) and virtual reality-based therapy (VRT) are common interventions.
- The combined effects of VRT and BFR on older women's physiological and perceptual responses remain unstudied.
Purpose of the Study:
- To assess autonomic and hemodynamic changes after VRT with BFR (VRT-BFR) in older women.
- To evaluate perceptual responses during and after VRT-BFR exercise recovery.
Main Methods:
- A randomized crossover trial involving 17 older women.
- Interventions included VRT-BFR (40% occlusion), VRT alone, and a control group, with a 7-day washout period.
- Hemodynamic (heart rate, blood pressure, double product) and autonomic (RR intervals) parameters were monitored during and after exercise.
Main Results:
- In the VRT-BFR group, RR intervals decreased, while heart rate and double product increased during recovery.
- No significant differences were found between groups or in group-time interactions for the measured outcomes.
- The VRT-BFR intervention did not lead to autonomic, hemodynamic, or perceptual imbalance post-exercise.
Conclusions:
- Virtual reality-based therapy combined with blood flow restriction is safe for older women.
- This combined therapy does not induce autonomic, hemodynamic, or perceptual instability during post-exercise recovery.

