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ExF-SVM: Exhaustive feature selection with support vector machine algorithm for brain stroke prediction
Prasannavenkatesan Theerthagiri1, A Usha Ruby2, George Chellin Chandran J3
1Department of Computer Science and Engineering, GITAM School of Technology, GITAM University Bengaluru, Bengaluru, India.
Computers in Biology and Medicine
|October 7, 2025
Summary
This study introduces an explainable AI model for brain stroke prediction, improving accuracy by 4-14% and F1 score by 5-15%. The novel Exhaustive Feature Selection with Support Vector Machine algorithm enhances clinical decision-making.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Healthcare
- Machine Learning for Disease Prediction
Background:
- Brain stroke prediction is critical for patient outcomes but challenged by AI's "black box" nature.
- Explainable AI (XAI) aims to bridge the gap between AI potential and clinical trust by enhancing model interpretability.
- Timely and accurate brain stroke prediction is essential to prevent severe patient harm and improve treatment efficacy.
Purpose of the Study:
- To propose a novel feature selection technique for identifying crucial characteristics in brain stroke prediction.
- To develop and assess an efficient brain stroke risk detection model using explainable AI.
- To enhance the accuracy and reliability of brain stroke prediction models in clinical settings.
Main Methods:
- Development and evaluation of an Exhaustive Feature Selection with Support Vector Machine (ExF-SVM) algorithm.
- Utilizing feature selection to determine the most impactful characteristics for brain stroke risk.
- Assessing model performance using metrics such as Receiver Operating Characteristics (ROC) curve, sensitivity, specificity, and F1-Score.
Main Results:
- The proposed ExF-SVM algorithm demonstrated improved classification accuracy by 4-14% compared to existing models.
- The F1 score saw a significant enhancement of 5-15% with the implemented methodology.
- The results highlight the effectiveness of the novel feature selection technique in improving brain stroke prediction.
Conclusions:
- The developed ExF-SVM algorithm offers a more interpretable and accurate approach to brain stroke prediction.
- This explainable AI model can enhance clinical decision-making and patient care in stroke management.
- The findings suggest significant contributions and ramifications for healthcare through advanced AI applications.
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