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Related Experiment Video

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Sound Source Localization Testing in Single-sided Deafness Following Bone Conduction Intervention

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The Era "or Error" of Second Localization Procedures.

Nicole Nelson¹, Jennifer Den¹, Roi Weiser²

¹Department of Surgery, University of Texas Medical Branch, Galveston, Texas, USA.

The Breast Journal

|October 8, 2025

Summary

This summary is machine-generated.

Fluoroscopic intraoperative neoplasm detection (FIND) offers a more accurate breast cancer localization method than radar (R) localization, reducing positive margin rates. This technique eliminates a second procedure, potentially improving patient comfort and surgical outcomes.

Keywords:

fluoroscopic intraoperative neoplasia detection fluoroscopic localization margin positivity re-excision rate

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Area of Science:

Oncology
Radiology
Surgical Oncology

Background:

Post-biopsy clips are often distant from the original tumor site.
Existing localization methods like radar (R) localization may increase this distance.
Fluoroscopic intraoperative neoplasm detection (FIND) aims to localize the biopsy clip directly during surgery.

Purpose of the Study:

To evaluate the feasibility of FIND for intraoperative localization.
To compare the positive margin rates between FIND and R localization.
To assess the impact of localization accuracy on surgical outcomes.

Main Methods:

Retrospective review of patients undergoing partial mastectomy (September 2016 - August 2023).
Comparison of outcomes between R localization and FIND groups.
Calculation of distance between biopsy clip and localization device using the Pythagorean theorem.

Main Results:

FIND group: 3% positive margins (6/161) vs. R group: 12% positive margins (7/55) (p=0.01).
Average distance to clip was greater in positive margin cases (19.1mm) than negative margin cases (12.45mm) for R localization (p=0.09).
FIND significantly reduced positive margin rates compared to R localization.

Conclusions:

FIND is a feasible and effective intraoperative localization technique.
FIND demonstrates a significantly lower positive margin rate than R localization.
Eliminating a second localization procedure with FIND may improve tumor-free margins and patient experience.