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Related Concept Videos

Anatomy of the Genitourinary System II: Bladder and Urethra01:19

Anatomy of the Genitourinary System II: Bladder and Urethra

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The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...
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Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
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Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
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The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
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Related Experiment Video

Updated: Jan 6, 2026

A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
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A Novel Artificial Detrusor System and Preliminary Experimental Study.

Mao Yin1, Li Xiao1

  • 1School of Electromechanical Engineering, Guangdong University of Technology, Guangzhou, China.

Artificial Organs
|October 8, 2025
PubMed
Summary

A new artificial detrusor system using shape memory alloy (SMA) springs and transcutaneous energy transfer (TET) shows promise for treating neurogenic bladder. The system successfully induced bladder voiding in animal studies, offering a simpler design for future assistive solutions.

Keywords:
TETanimal studiesartificial detrusorshape memory alloysimulated experiments

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Urology

Background:

  • Neurogenic bladder significantly impacts quality of life and poses health risks.
  • Current treatments for neurogenic bladder are limited and often ineffective.
  • Existing artificial detrusor systems face challenges in structural complexity and biomechanical compatibility.

Purpose of the Study:

  • To develop a novel artificial detrusor system for neurogenic bladder.
  • To mimic physiological urine storage and voiding mechanisms.
  • To overcome limitations of current artificial detrusor designs.

Main Methods:

  • Designed an artificial detrusor system utilizing shape memory alloy (SMA) springs.
  • Implemented transcutaneous energy transfer (TET) for wireless power.
  • Evaluated system performance through simulations and animal studies.

Main Results:

  • Excitation voltage, SMA specifications, and energization duration affected voiding rate and temperature.
  • The prototype successfully induced bladder voiding in animal models.
  • Demonstrated the feasibility of SMA-driven actuation and TET.

Conclusions:

  • Presents a promising artificial detrusor system for neurogenic bladder.
  • The system offers a simple structure and feasible working principle.
  • Provides a new technical pathway for assistive solutions for neurogenic bladder dysfunction.