Inspection confirmed mold damage in schools and new use of drugs for airway obstruction: A cohort study

Juha Pekkanen1,2, Martin Täubel2,3, Lauri Lehtimäki4,5

  • 1Department of Public Health, University of Helsinki, Helsinki, Finland.

Plos One
|October 8, 2025
PubMed
Abstract

Insights

Mold damage in Finnish schools did not increase asthma risk in students. Some limited evidence suggested a link to obstructive airway disease drug use in primary students, but not asthma development.

Area of Science:

  • Environmental Health
  • Pediatric Respiratory Health
  • Building Science

Background:

  • Indoor mold exposure in schools is a public health concern.
  • Previous studies suggest links between mold and respiratory issues, but evidence on dose-response relationships and specific outcomes like asthma onset is inconsistent.
  • Understanding environmental factors in schools is crucial for student health.

Purpose of the Study:

  • To investigate the association between the extent and severity of mold damage in Finnish school buildings and the risk of new-onset asthma and new use of drugs for obstructive airway diseases among students.
  • To determine if a dose-response relationship exists between mold damage levels and these health outcomes.

Main Methods:

  • A cohort of 30,418 Finnish students from 110 schools was followed.
  • Mold damage in school buildings was assessed based on technical inspections up to 2021.
  • New asthma cases (1,035) and drug use for obstructive airway diseases (3,162) were identified through drug purchases by 2019.
  • Multilevel Cox models were used, adjusting for confounders from the Medical Birth Register.

Main Results:

  • Extensive mold damage was prevalent, with varying degrees across the 110 schools.
  • No significant association was found between mold damage and new-onset asthma in the general student population or those with pre-existing airway problems.
  • A potential association was observed among primary school students for new drug use for obstructive airway diseases, with the highest risk noted in buildings with limited mold damage.

Conclusions:

  • The study's findings suggest that assessing the extent and severity of mold damage within school building structures does not reliably identify buildings posing an increased risk for students developing asthma.
  • Further research may be needed to explore potential links between specific types of mold, other indoor environmental factors, and respiratory health outcomes in school settings.