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The Association Between Age at First Live Birth and Depression: Results From NHANES 2005-2018
Ali Kolahdooz1,2, Fatemeh Movahed3, Mohsen Yousefi1
1Student Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Depression and Anxiety
|October 9, 2025
Summary
Having a first live birth at a younger age is linked to higher depression rates in women. Delaying first birth is associated with a significant decrease in depression prevalence.
Area of Science:
- Reproductive Health
- Mental Health
- Public Health
Background:
- Investigates the link between age at first live birth and depression in women.
- Utilizes data from the National Health and Nutritional Examination Surveys (NHANES) from 2005-2018.
Purpose of the Study:
- To examine the association between age at first live birth and depression among women aged 12 years or older.
- To understand the impact of reproductive timing on mental health outcomes.
Main Methods:
- Cross-sectional study design.
- Analysis of data from 10,399 participants.
- Depression assessed using the Patient Health Questionnaire (PHQ-9).
- Age at first live birth categorized as <18, 18-25, and >25 years.
Main Results:
- Women with depressive symptoms were more likely to be single, have lower socioeconomic status, smoke, and have sleep disorders.
- Younger age at first live birth correlated with higher depression prevalence.
- First birth at 18-25 (47% decrease) or >25 (76% decrease) significantly reduced depression risk.
- An 11% depression reduction for every year increase in age at first birth was observed.
- Multivariate analyses confirmed a significant association after adjusting for confounding factors.
Conclusions:
- Age at first live birth is significantly associated with depression in women.
- Reproductive history, specifically age at first birth, should be considered in mental health assessments.
- Sociodemographic and lifestyle factors play a multifaceted role in this relationship.
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