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Updated: Jan 15, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Published on: July 11, 2013

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Advanced Combination Therapy with Tofacitinib and Biologic Agents for Psoriasis and Psoriatic Arthritis: A Case

Cathrine Dawn Büttner Elgaard1,2, Trine Bay Laurberg2,3, Jørgen Agnholt2,4

  • 1Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.

Case Reports in Dermatology
|October 9, 2025
PubMed
Abstract

Insights

Combining Janus kinase (JAK) inhibitors with biologics showed varied effectiveness for psoriatic disease, improving skin and joint symptoms but not inflammatory bowel disease. Further research is needed to confirm safety and efficacy.

Area of Science:

  • Dermatology
  • Rheumatology
  • Gastroenterology

Background:

  • Psoriatic disease treatment is complex, with many patients unresponsive to current therapies.
  • Biologics and Janus kinase (JAK) inhibitors are used individually, but combination data is limited.
Keywords:
BiologicsJAK inhibitorsPsoriasisPsoriatic arthritis

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