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Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids
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Glucocorticoids-Induced Adrenal Insufficiency With Intractable Vomiting: A Case Report.
Yamei Ran1, Yongmei Peng1, Juan Xiao1
1Department of Gastroenterology and Hepatology Thirteenth People's Hospital of Chongqing Chongqing China.
Clinical Case Reports
|October 9, 2025
Summary
Glucocorticoid-induced adrenal insufficiency can mimic gastrointestinal issues. Prompt hydrocortisone treatment resolved symptoms in an elderly male patient, demonstrating the importance of considering endocrine causes for persistent digestive problems.
Area of Science:
- Endocrinology
- Gastroenterology
- Internal Medicine
Background:
- An 80-year-old male presented with a year of reflux and vomiting, fatigue, and appetite loss.
- Standard gastrointestinal and neurological workups were negative.
- Chronic glucocorticoid use was a key historical factor.
Purpose of the Study:
- To investigate the potential link between chronic glucocorticoid use and the patient's persistent gastrointestinal symptoms.
- To evaluate the efficacy of hydrocortisone replacement therapy.
Main Methods:
- Clinical presentation analysis
- Comprehensive diagnostic evaluation (imaging, lab tests)
- Therapeutic trial with hydrocortisone
Main Results:
- Glucocorticoid-induced adrenal insufficiency was diagnosed.
- One month of hydrocortisone treatment led to significant symptom resolution.
- The patient remained symptom-free six months after discontinuing corticosteroid therapy.
Conclusions:
- Glucocorticoid-induced adrenal insufficiency should be considered in patients with unexplained gastrointestinal symptoms and a history of chronic glucocorticoid use.
- Hydrocortisone replacement therapy is effective in managing this condition.
- Early diagnosis and treatment can significantly improve patient outcomes.
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