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Optical Performance and Refractive Outcomes of a New Monofocal Intraocular Lens With Intermediate Optimized Optics.

Marcela Feltrin de Barros1,2, Larissa Gouvea1, Christine Hill1

  • 1Medical University of South Carolina, Storm Eye Institute, South Carolina.

Journal of Refractive Surgery (Thorofare, N.J. : 1995)
|October 9, 2025
PubMed
Summary

This study shows a new monofocal intraocular lens (IOL) provides excellent distance vision and useful intermediate/near vision. Automated refraction and wavefront analysis confirm good refractive outcomes and minimal aberrations after cataract surgery.

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Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Cataract surgery requires precise intraocular lens (IOL) implantation for optimal visual outcomes.
  • Traditional monofocal IOLs offer good distance vision but limited intermediate and near visual function.

Purpose of the Study:

  • To evaluate the refractive outcomes, defocus curve, wavefront analysis, and automated refraction of a novel monofocal IOL.
  • Assess the performance of an IOL with higher-order aspheric coefficients and controlled curvature change.

Main Methods:

  • Prospective observational study of 29 patients undergoing cataract surgery with enVista Aspire IOL implantation.
  • Measured uncorrected (UDVA), corrected (CDVA), distance-corrected intermediate (DCIVA), and distance-corrected near (DCNVA) visual acuity.
  • Analyzed defocus curve, wavefront aberrations, refractive prediction error, and automated/manifest spherical equivalent (MRSE).

Main Results:

  • Excellent distance visual acuity: Mean UDVA 20/22, Mean CDVA 20/20.
  • Useful intermediate and near vision: Mean DCIVA 20/34, Mean DCNVA 20/38.
  • Achieved emmetropia (0.02 ± 0.29 D MRSE), with 96.6% of eyes within ±0.50 D; minimal 4th-order spherical aberration (0.08-0.15 µm).

Conclusions:

  • The novel enhanced monofocal IOL provides excellent distance vision with functional intermediate and near visual capabilities.
  • Wavefront analysis confirmed minimal postoperative spherical aberration, indicating good optical quality.
  • Automated refraction results were consistent with emmetropia, supporting the IOL's refractive predictability.