Related Experiment Video
Updated: Jan 15, 2026

Adult Mouse Venous Hypertension Model: Common Carotid Artery to External Jugular Vein Anastomosis.
Published on: January 27, 2015
Spontaneous thrombosis of drainage vein in cavernoma-associated developmental venous anomaly
Miguel Ossuna1, Pedro Tadao Hamamoto Filho2, Marco Antônio Zanini2
1São Paulo State University, São Paulo, Brazil. miguel.ossuna@unesp.br.
Abstract:
A 57-year-old male with multiple supratentorial and infratentorial cavernomas presented with subacute-onset headache, tinnitus, and worsening neurological deficits. Imaging revealed spontaneous thrombosis of a previously documented developmental venous anomaly (DVA) in the posterior fossa, resulting in cerebellar parenchymal hemorrhage and posterior fossa hypertension consistent with venous infarction. This case highlights the rare occurrence of spontaneous DVA thrombosis, emphasizing its potential for severe complications, such as venous ischemic infarction, parenchymal hemorrhage, venous congestion, or subarachnoid hemorrhage, as well as the importance of sequential imaging in documenting pathological progression.
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