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Neurulation

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...

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Related Experiment Video

Updated: Jan 15, 2026

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

Published on: August 19, 2020

Innovation in neonatology - Authors' reply

Matheus van Rens¹, Robin van der Lee¹, Giovanni Barone²

¹Neonatal Intensive Care Unit, Radboudumc Amalia Children's Hospital, Nijmegen, Netherlands.

The Lancet. Child & Adolescent Health

|October 9, 2025

Summary

No abstract available in PubMed .

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