Complete genome sequence of Serratia marcescens MPHSM1, isolated from a patient with necrotizing fasciitis

Mako Mamiya1, Akira Sata2, Toshiki Inoue1

  • 1Department of General Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.

PubMed

Insights

Serratia marcescens is a pathogen causing infections. This study presents the full genome sequence of the MPHSM1 strain, linked to necrotizing fasciitis, aiding in understanding infection mechanisms.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Serratia marcescens is an opportunistic pathogen.
  • It causes hospital-acquired and community-acquired infections.
  • Necrotizing fasciitis is a severe infection.

Purpose of the Study:

  • To report the complete genome sequence of Serratia marcescens strain MPHSM1.
  • To provide genomic data for a strain causing necrotizing fasciitis.

Main Methods:

  • Whole-genome sequencing of Serratia marcescens strain MPHSM1.
  • Bioinformatic analysis of the genome sequence.

Main Results:

  • The complete genome sequence of S. marcescens MPHSM1 was determined.
  • The genome size is 5,022,671 base pairs.
  • The G+C content of the genome is 59.76%.

Conclusions:

  • The genome sequence provides a valuable resource for studying S. marcescens.
  • Understanding the genome may help elucidate mechanisms of necrotizing fasciitis.
  • Further research can utilize this genomic data to explore virulence factors and develop targeted therapies.