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Updated: Jan 15, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
Complete genome sequence of Serratia marcescens MPHSM1, isolated from a patient with necrotizing fasciitis
Mako Mamiya1, Akira Sata2, Toshiki Inoue1
1Department of General Medicine, Miyazaki Prefectural Miyazaki Hospital, Miyazaki, Japan.
Abstract:
Serratia marcescens is an opportunistic pathogen that causes a variety of hospital-acquired and community-acquired infections. Here, we report the complete genome sequence of S. marcescens strain MPHSM1 responsible for necrotizing fasciitis. The genome is 5,022,671 bp long, with a G+C content of 59.76%.
Insights
Serratia marcescens is a pathogen causing infections. This study presents the full genome sequence of the MPHSM1 strain, linked to necrotizing fasciitis, aiding in understanding infection mechanisms.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Serratia marcescens is an opportunistic pathogen.
- It causes hospital-acquired and community-acquired infections.
- Necrotizing fasciitis is a severe infection.
Purpose of the Study:
- To report the complete genome sequence of Serratia marcescens strain MPHSM1.
- To provide genomic data for a strain causing necrotizing fasciitis.
Main Methods:
- Whole-genome sequencing of Serratia marcescens strain MPHSM1.
- Bioinformatic analysis of the genome sequence.
Main Results:
- The complete genome sequence of S. marcescens MPHSM1 was determined.
- The genome size is 5,022,671 base pairs.
- The G+C content of the genome is 59.76%.
Conclusions:
- The genome sequence provides a valuable resource for studying S. marcescens.
- Understanding the genome may help elucidate mechanisms of necrotizing fasciitis.
- Further research can utilize this genomic data to explore virulence factors and develop targeted therapies.

