Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypodermis01:02

Hypodermis

7.2K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adipose tissue as a humoral-neuronal hub in metabolic regulation.

Nature reviews. Endocrinology·2026
Same author

Atg8 orchestrates stress-responsive chromatin programs across immunity and metabolism.

bioRxiv : the preprint server for biology·2026
Same author

A New World disease: Dual diagnostic challenges in travelers returning from Costa Rica.

Dermatology online journal·2026
Same author

15-PGDH inhibition promotes muscle repair and strength recovery during GLP-1 receptor agonist-induced weight loss.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Career Advancement Challenges for Women in Tenure Versus Clinical Tracks in Academic Medicine: Cross-Sectional Survey Study.

JMIR formative research·2026
Same author

15-PGDH Inhibition Overcomes Muscle Regenerative Deficit Seen With GLP1-Receptor Agonist-Induced Weight Loss.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Jan 15, 2026

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice
05:34

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice

Published on: January 24, 2025

2.6K

Advances in Adipose Tissue Biology.

Silvia Corvera1, Akhila Rajan2, Kristy L Townsend3

  • 1Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA.

Endocrine Reviews
|October 10, 2025
PubMed
Summary

Adipose tissue is vital for human health, regulating energy and communicating with organs. Its dysfunction links to obesity-related diseases, but new research reveals its complex roles and therapeutic potential.

Keywords:
adipocytesadipose tissuedepotsenergy homeostasisobesitytype 2 diabetes

More Related Videos

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging
10:10

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging

Published on: August 19, 2020

8.1K
Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
06:08

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

2.8K

Related Experiment Videos

Last Updated: Jan 15, 2026

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice
05:34

Isolation and Culturing of Primary Murine Adipocytes from Lean and Obese Mice

Published on: January 24, 2025

2.6K
Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging
10:10

Exploring Adipose Tissue Structure by Methylsalicylate Clearing and 3D Imaging

Published on: August 19, 2020

8.1K
Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator
06:08

Author Spotlight: Semi-Automated Isolation of the Stromal Vascular Fraction from Murine White Adipose Tissue Using a Tissue Dissociator

Published on: May 19, 2023

2.8K

Area of Science:

  • Physiology
  • Endocrinology
  • Metabolic Diseases

Background:

  • Adipose tissue, once considered inert, is now recognized as a dynamic endocrine organ.
  • Dysfunction of adipose tissue is a key driver of obesity-associated diseases like type 2 diabetes, cardiovascular disease, liver disease, and cancer.
  • Adipocytes are crucial for energy homeostasis and interorgan communication, including with the brain.

Purpose of the Study:

  • To review major scientific advancements in understanding adipose tissue's role in health and disease.
  • To highlight the specialized functions of distinct adipose depots.
  • To underscore the potential of new technologies in identifying therapeutic targets.

Main Methods:

  • Review of key scientific literature and discoveries.
  • Emphasis on advancements enabled by technologies like single-cell RNA sequencing.
  • Acknowledgment of funding sources, particularly the National Institute of Diabetes, Digestive and Kidney Diseases.

Main Results:

  • Adipose tissue plays a pivotal role in regulating human physiology.
  • Distinct adipose depots exhibit specialized functions influenced by development, sex, and aging.
  • Single-cell RNA sequencing is revealing depot-specific mechanisms.

Conclusions:

  • Adipose tissue is central to human health and disease.
  • Understanding depot-specific functions is crucial for therapeutic development.
  • Continued research, supported by institutions like NIDDK, is essential for advancing the field.