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Robot-Assisted Interval Cholecystectomy Is Not Inferior to Laparoscopic Interval Cholecystectomy in Advanced
Ikemsinachi C Nzenwa1, Ritwik Sanyal2, Yasmin Arda1
1Division of Trauma, Department of Surgery, Emergency Surgery & Surgical Critical Care, Massachusetts General Hospital, Boston, Massachusetts.
The Journal of Surgical Research
|October 10, 2025
Summary
Robot-assisted interval cholecystectomy (IC) after percutaneous cholecystostomy (PCT) shows similar complication rates to laparoscopic IC. However, robot-assisted IC is linked to higher healthcare costs without improving patient outcomes.
Area of Science:
- Surgical Innovation
- Minimally Invasive Surgery
- Health Economics
Background:
- Robot-assisted surgery is increasingly used but linked to higher bile duct injury rates.
- Careful patient selection is crucial for robot-assisted procedures.
- This study compares laparoscopic and robot-assisted interval cholecystectomy (IC) after percutaneous cholecystostomy (PCT).
Purpose of the Study:
- To compare complication rates and healthcare utilization between laparoscopic and robot-assisted IC.
- To evaluate outcomes in patients undergoing IC after PCT.
- To assess the impact of center volume on outcomes.
Main Methods:
- Analysis of the 2016-2019 Nationwide Readmissions Database (NRD).
- Inclusion of adult patients who underwent PCT for cholecystitis and subsequent IC (laparoscopic or robot-assisted).
- 2:1 propensity-matched analysis comparing composite mortality-morbidity, length of stay, discharge rates, and costs; subgroup analysis of high-volume centers.
Main Results:
- No significant difference in composite mortality-morbidity rates between robot-assisted and laparoscopic IC (37.8% vs. 34.3%).
- Similar length of stay and nonroutine discharge rates for both approaches.
- Robot-assisted IC was associated with significantly higher hospital costs ($17,077 vs. $13,531).
Conclusions:
- Robot-assisted and laparoscopic IC offer comparable clinical outcomes in patients with complex gallbladders or advanced cholecystitis.
- Robot-assisted IC does not increase the risk of adverse outcomes.
- Robot-assisted IC is associated with higher healthcare costs compared to laparoscopic IC.

