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Updated: Jan 15, 2026

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
Published on: December 4, 2015
The evolving threat of drug-resistant malaria in a globalized world
Shruti Shukla1, Dr Ashutosh Mani1
1Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj-211004, India.
Objective:
Malaria is one of the most threatening parasitic infectious diseases of humans, causing major health and economic burden, particularly in low- and middle-income countries. Plasmodium falciparum is the most lethal parasite species that causes the disease and is responsible for the highest number of malaria-related deaths.
Methods:
Despite the availability of antimalarial drugs and preventive measures, malaria continues to threaten millions of people. Malaria control programs face several challenges due to the spread of drug-resistant parasites. Understanding the mechanisms of action of antimalarial drugs and the genetic basis of resistance is therefore essential.
Results:
This review highlights the molecular mechanisms of drug resistance against malaria, its global impact, and the urgent need for real-time surveillance systems.
Conclusion:
Deeper understanding about the drug resistance in the parasites may be further helpful in providing improved treatment and devising more effective control strategies.
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