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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
Published on: September 16, 2020
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[Primary hyperoxaluria-induced bilateral oxalate retinopathy: a case report]
1Xi'an People's Hospital (Xi'an Fourth Hospital), Shaanxi Eye Hospital, Xi'an Key Laboratory of Digital Medical Technology of Ophthalmologic Imaging, Xi'an 710004, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|October 10, 2025
Summary
Primary hyperoxaluria, a genetic condition, can cause oxalate crystals in the retina, leading to vision loss. Early diagnosis combining genetic tests and imaging is crucial for managing this rare eye disease.
Area of Science:
- Ophthalmology
- Medical Genetics
- Nephrology
Background:
- Primary hyperoxaluria (PH) is a rare metabolic disorder characterized by excessive oxalate production.
- Ocular manifestations of PH, such as oxalate retinopathy, are increasingly recognized.
- Genetic mutations, particularly in the AGXT gene, are the primary cause of PH.

