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Transforming Cancer Drug Access: Insights Into Utilization and Clinician Satisfaction in a Statewide Cancer Drug
Emily R Mackler1,2, Siobhan Norman1
1YesRx, Ann Arbor, MI.
JCO Oncology Practice
|October 11, 2025
Summary
The YesRx Network, a cancer drug repository, provided $17.59 million in free cancer medications to 1,124 patients, reducing waste and improving access, especially in rural Michigan areas.
Area of Science:
- Oncology
- Health Services Research
- Pharmacoeconomics
Background:
- High-cost cancer therapies create financial burdens for patients.
- Simultaneously, medication waste is a growing concern in cancer care.
Purpose of the Study:
- To evaluate the YesRx Network, a statewide cancer drug repository (CDR) in Michigan.
- To assess its impact on patient access to medications, waste reduction, and participant satisfaction.
Main Methods:
- Retrospective review of CDR data from the YesRx Network over 24 months.
- Analysis of donation and dispensing metrics across 105 partner sites.
- Cross-sectional survey of healthcare participants regarding program experiences and operational impact.
Main Results:
- Over $26.96 million in cancer medications were donated, with over 100,000 viable pills.
- $17.59 million worth of free prescriptions were dispensed to 1,124 patients.
- Recipients spanned 90% of Michigan counties, with 40% in rural areas; 84% of participants felt unable to offer CDR programming without YesRx support.
Conclusions:
- The YesRx Network model effectively expands equitable access to high-cost cancer drugs.
- This statewide CDR approach significantly reduces medication waste.
- The program enhances oncology clinician support and offers a replicable model for national implementation.
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