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A Short Patient-Reported Outcome Measure for Oral Anticancer Agents: Multicenter Observational Study.

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This summary is machine-generated.

A rapid patient-reported outcome measure (RapidPRO) for oral anticancer agents (OAAs) identified frequent symptoms and 28% nonadherence. This tool helps practices identify patients needing support for symptom management and medication adherence.

Keywords:
adverse effectsmedication adherenceoral anticancer agentpatient-reported outcomessymptoms

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Area of Science:

  • Oncology
  • Patient-Reported Outcomes
  • Pharmacology

Background:

  • The Michigan Oncology Quality Consortium developed RapidPRO, a patient-reported outcome measure for oral anticancer agents (OAAs).
  • The goal was to create a single instrument for all OAAs to simplify implementation in clinical practice.
  • This contrasts with common cancer-specific approaches.

Purpose of the Study:

  • To describe the clinical use of RapidPRO in oncology practices.
  • To quantify symptom burden, patient confidence in symptom management, and OAA medication adherence.
  • To assess RapidPRO's utility in capturing patient experiences with OAAs.

Main Methods:

  • An observational study was conducted across 6 oncology practices from July 2016 to December 2018.
  • RapidPRO was used to assess patient symptoms, confidence, and OAA medication adherence.
  • Data from 2252 completed RapidPROs by 695 patients were analyzed.

Main Results:

  • Over half (53.9%) of completed RapidPROs reported at least one moderate to severe symptom.
  • Medication nonadherence was reported in 28% of patients.
  • The most common reason for nonadherence was experiencing side effects; 46.5% of patients reported a most bothersome symptom.

Conclusions:

  • The RapidPRO measure effectively captures symptom burden and medication nonadherence in patients on OAAs.
  • Implementation of RapidPRO allows practices to identify patients experiencing significant symptoms or nonadherence.
  • This facilitates timely interventions to improve patient care and treatment outcomes.