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Talat Jabeen^1,2,3, David Horn^1,2,3, Mark W Pettet⁴

¹Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, Washington, USA.

Ear and Hearing

|October 13, 2025

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This summary is machine-generated.

This study shows electroencephalography (EEG) can detect the acoustic change complex (ACC) in infants, matching behavioral discrimination of spectral ripple stimuli. This EEG measure shows potential for assessing speech sound discrimination in infants as young as 3 months.

Area of Science:

Auditory Neuroscience
Developmental Audiology
Clinical Electrophysiology

Background:

Assessing speech sound discrimination in infants with hearing aids or cochlear implants is challenging due to limited clinical methods.
Spectral ripple discrimination is a nonlinguistic measure correlating with speech perception in children and adults.
Electrophysiological responses to spectral ripple stimuli offer a potentially feasible clinical tool for infants.

Purpose of the Study:

To adapt a behavioral spectral ripple envelope inversion discrimination paradigm for electroencephalography (EEG) in infants.
To investigate if the acoustic change complex (ACC) detection in infants matches prior behavioral discrimination of spectral ripple stimuli.
To evaluate the ACC as an objective measure for infant speech sound discrimination.

Keywords:

Acoustic change complex Electrophysiology Infant assessment Spectral ripple envelope inversion

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Main Methods:

Utilized spectral ripple stimuli with 1 ripple-per-octave (RPO) and 8 RPO densities, modulated with a 10 dB depth.
Elicited the acoustic change complex (ACC) by imposing a spectral envelope inversion mid-stimulus (at 1 second).
Recorded 32-channel EEG from adult and 3-month-old infant participants exposed to both 1 RPO and 8 RPO conditions.

Main Results:

Group-level ACC detection occurred only for the 1 RPO stimulus, not the 8 RPO stimulus, in both infants and adults.
Onset responses were detected for both ripple densities, confirming stimulus detection.
Individual ACC detection rates were 81% for infants and 73% for adults in the 1 RPO condition, significantly higher than the 8 RPO condition.

Conclusions:

EEG ACC detection correlates with behavioral spectral ripple discrimination abilities.
The ACC shows potential for estimating infant discrimination thresholds, elicited by suprathreshold (1 RPO) but not subthreshold (8 RPO) acoustic changes.
The ACC may serve as an objective measure for stimulus discriminability in 3-month-old infants, warranting further research for clinical application.