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The Role of Medical Therapy in Hypertrophic Cardiomyopathy: An Updated Review
Jung-Won Lee1, Kyeong-Hyeon Chun1, Eui-Young Choi1
1Division of Cardiology, Heart Center, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, South Korea.
Abstract:
This review highlights recent advances in hypertrophic cardiomyopathy (HCM) treatment, focusing on how to effectively implement both traditional and novel pharmacologic strategies in clinical practice. Traditional medications like beta-blockers and calcium channel blockers continue to play a critical role. However, new treatments, such as cardiac myosin inhibitors, provide an innovative approach for relieving symptoms, especially in obstructive HCM cases. Emerging therapies, including sodium-glucose cotransporter 2 inhibitors, sacubitril/valsartan, and ninerafaxstat, show promising benefits. Proper management of related conditions such as atrial fibrillation and heart failure is also essential. A comprehensive approach that considers individual patient characteristics and the specific subtype of HCM is essential for achieving optimal outcomes.
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