Artifactual Hypocalcemia from Gadodiamide Interference.
Clinical Laboratory
|October 13, 2025
Summary
Gadolinium-based contrast agents can cause falsely low calcium levels in lab tests. Recognizing this interference prevents unnecessary medical treatments and ensures accurate patient care.
Area of Science:
- Clinical Chemistry
- Medical Diagnostics
- Radiology
Background:
- Gadolinium-based contrast agents (GBCAs) are frequently used in MRI scans.
- GBCAs, like gadodiamide, can interfere with specific laboratory assays.
- This interference can lead to inaccurate patient test results, particularly for calcium levels.
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