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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

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Published on: December 6, 2016

Managing Complete Concentric Collapse in Obstructive Sleep Apnea: A Narrative Review.

Kalin R Sorenson¹, Abigail Fish², Benjamin D Brooks³

¹Otolaryngology, Rocky Vista University College of Osteopathic Medicine, Ivins, USA.

|October 13, 2025

Summary

This summary is machine-generated.

Obstructive sleep apnea with complete concentric collapse is hard to treat. Bilateral hypoglossal nerve stimulation may offer a new solution for airway stability, reducing the need for invasive surgeries.

Keywords:

bilateral hypoglossal nerve stimulation complete concentric collapse concentric collapse failure of cpap genio device inspire device levanova device obstructive sleep apnoea unilateral hypoglossal nerve stimulation uvulopalatopharyngoplasty

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A Model to Simulate Clinically Relevant Hypoxia in Humans

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

Area of Science:

Sleep Medicine
Otolaryngology
Surgical Innovation

Background:

Obstructive sleep apnea (OSA) is a common disorder with serious health risks.
Complete concentric collapse (CCC) of the airway presents unique treatment challenges.
Conventional therapies like CPAP and HGNS are often less effective in CCC cases.

Purpose of the Study:

To review current surgical treatments for OSA, focusing on CCC.
To evaluate the limitations of hypoglossal nerve stimulation (HGNS) in CCC patients.
To explore the potential of bilateral HGNS (B-HGNS) as an alternative therapy.

Main Methods:

Narrative review of existing literature on OSA surgical treatments.
Critical analysis of studies concerning HGNS efficacy and contraindications in CCC.
Exploration of B-HGNS mechanisms and potential benefits.

Main Results:

Standard OSA surgeries (UPPP, ESP, MMA) have limitations in CCC.
HGNS effectiveness is debated in CCC due to airway dynamics.
B-HGNS shows promise for synchronizing genioglossus muscles and enhancing airway stability.

Conclusions:

Treating OSA with CCC requires specialized approaches.
B-HGNS presents a potential advancement for improving airway stability in CCC patients.
Further research is needed to validate B-HGNS and develop less invasive OSA treatments.