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Published on: November 19, 2016
Environmental pollutants and allergic sensitization: A systematic literature review
Eric Lopez-Retana1, Zoe Gomez-Mendoza1, Jaime Guerrero-Quezada1
1Facultad Mexicana de Medicina, Universidad La Salle México, Tlalpan, Mexico City, Mexico.
Background:
Exposure to environmental pollutants has been associated with an increased risk of respiratory and allergic diseases.
Objective:
To describe the interactions between common pollutants and the immune system and their association with allergic diseases.
Methods:
A systematic literature review was conducted using PubMed, Clinical Key, Redalyc, MEDLINE, and SciELO for studies published between 2018 and 2024.
Results:
Evidence shows that pollutants such as PM2.5 , PM10 , NO2 , CO, and ozone trigger oxidative stress, inflammatory responses, and epithelial damage, facilitating allergic sensitization, asthma, rhinitis, and dermatitis.
Conclusions:
Exposure to environmental pollutants plays a key role in the development and exacerbation of allergic diseases, highlighting the need for preventive measures.
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