Astrocytes as Active Participants in Memory

Recent research has revealed the crucial role of astrocytes in memory processes, challenging the traditional view of exclusively neuronal-based cognitive functions. This review summarizes current findings on astrocytic involvement in memory, focusing on their interactions with neurotransmitters, various biomolecules, and neurons in different brain regions. We include studies that discuss how astrocytes modulate synaptic transmission and contribute to plasticity, thereby influencing memory formation, consolidation, and recall. We conclude by providing an overview of advanced techniques such as optogenetics, chemogenetics, calcium imaging, and engram research, which have provided new insights into the function of astrocytes and their role in memory processes.