Adoption of polyvinyl alcohol electrospinning materials for skin wound dressing

The effective treatment and repair of skin trauma has always been an important topic of medical research. As an advanced preparation method of nanofibers (NFs), electrospinning (ES) technology shows broad application prospects in the field of skin wound dressing. This review aims to systematically summarize and analyze the process and application research progress of PVA ES materials in skin wound dressing, and explore its mechanism and clinical application prospects in the process of wound healing. By consulting and analyzing the literature about PVA ES materials in recent years, the preparation process, structural properties, and application examples in skin wound dressing were focused on, and the latest experimental research and clinical data were combined to make a comprehensive review. The results suggested that PVA ES material had unique advantages in wound healing. NFs dressings with specific structure and properties can be prepared by adjusting ES parameters. PVA ES dressing not only has excellent physical barrier function, but also can regulate humidity, promote cell proliferation and angiogenesis, thus accelerating wound healing. In addition, the functionally modified PVA fiber dressing also suggested visible effects in antibacterial, anti-inflammatory, and other aspects. Visible progress has been made in the application of PVA ES materials in skin wound dressings. However, further optimization of its preparation process, improvement of functional properties, and large-scale clinical trial validation are still the key directions of future research. Through continuous innovation and improvement, PVA ES dressing is expected to play a greater role in the field of skin wound repair and promote the development of regenerative medicine.