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Response to Commentary on Evaluation of Intestinal Permeability in Children Diagnosed With Bronchiolitis in Pediatric

Abdullah Akkuş1, Ahmet Osman Kiliç1, Fatih Ercan2

  • 1Department of Pediatrics, Faculty of Medicine, Necmettin Erbakan University, Konya, Türkiye.

Pediatric Pulmonology
|October 15, 2025
PubMed
Abstract

No abstract available in PubMed .

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Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
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