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Updated: Jul 19, 2026

Production of Disulfide-stabilized Transmembrane Peptide Complexes for Structural Studies
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[In Vitro Reconstitution of the Staphylococcus aureus 50S Ribosomal Subunit-GTP-Binding Factor YsxC Complex for

A D Biktimirov1, M M Yusupov1,2,3, K S Usachev1,4

  • 1Kazan Federal University, Kazan, 420008 Russia.

Molekuliarnaia Biologiia
|October 15, 2025
PubMed
Summary

The bacterial GTP-binding protein YsxC is essential for large ribosomal subunit maturation. Without YsxC, immature subunits accumulate, preventing ribosome formation and causing cell death in Staphylococcus aureus.

Keywords:
GTP-binding proteinsribosomestructural biologytranslation

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