Predicting Intraocular Collamer Lens Vault in Myopic Patients With Shallow Anterior Chamber Using FedEYE Platform and
Zhanyu Su1, Zhaoxiang Wang2, Shanshan Wang2
1Aier Academy of Ophthalmology, Central South University, Changsha, Hunan, China.
Translational Vision Science & Technology
|October 15, 2025
Summary
Code-free artificial intelligence (AI) models effectively predicted vault in patients with shallow anterior chamber depth (ACD) undergoing implantable collamer lens (ICL) surgery. These AI tools offer promising advancements for surgical safety and efficacy.
Area of Science:
- Ophthalmology
- Artificial Intelligence
- Medical Imaging
Background:
- Shallow anterior chamber depth (ACD) presents challenges in implantable collamer lens (ICL) surgery.
- Accurate prediction of postoperative vault is crucial for optimizing surgical outcomes and patient safety.
Purpose of the Study:
- To evaluate the effectiveness of code-free artificial intelligence (AI) platforms, FedEYE and ChatGPT, in predicting vault in patients with shallow ACD undergoing ICL surgery.
- To compare the performance of different AI models and data combinations for vault prediction.
Main Methods:
- A retrospective study of 160 eyes with shallow ACD (<2.8 mm) was conducted.
- Two code-free AI models were developed: an integrated neural network (INN) using FedEYE with optical coherence tomography (OCT) images and examination data, and ChatGPT utilizing memory prompting.
- The models were trained and validated using multimodal preoperative data.
Main Results:
- The INN model, combining OCT images and examination data, achieved high accuracy (0.875), sensitivity (0.857), specificity (0.889), and AUC (0.873).
- Anterior chamber angle and spherical equivalent positively correlated with vault; age and white-to-white diameter showed negative correlation.
- ChatGPT, after memory prompting, demonstrated good performance with accuracy of 0.813 and AUC of 0.865.
Conclusions:
- Code-free AI tools like FedEYE and ChatGPT can be developed and deployed straightforwardly.
- These AI models show encouraging performance in predicting vault for shallow ACD patients, aiding surgical planning.
- Utilizing AI for vault prediction holds significant clinical potential for enhancing safety and efficacy in ICL surgeries for this patient group.
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