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When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
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Personality traits represent consistent patterns in behavior, thoughts, and emotions, reflecting an individual's tendencies across various situations. For example, extraversion, a well-known trait, manifests in individuals as talkative, energetic, and enthusiastic behaviors. These traits are stable over time, offering a reliable framework for predicting how people might act in different contexts. However, they do not define every moment of an individual's life. In contrast to traits,...
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Gregor Mendel's pioneering work on the principles of inheritance fundamentally transformed our understanding of how traits are transmitted from generation to generation. His experiments with pea plants laid the groundwork for the discovery of genes, discrete units within organisms that control heredity.
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Treatable Traits. Why, What, How?

Alvar Agusti1, Peter Gibson2, Mario Cazzola3

  • 1Cathedra Salud Respiratoria. Universitat Barcelona, Spain; Respiratory Institute, Clinic, Barcelona, Spain; FCRB-IDIBAPS, Barcelona, Spain; CIBERES (ISCiii), Spain.

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|October 15, 2025
PubMed
Summary
This summary is machine-generated.

Precision medicine offers personalized treatment for complex chronic airway diseases like asthma and COPD. This approach focuses on identifying and managing treatable traits for better patient outcomes.

Area of Science:

  • Pulmonology and Respiratory Medicine
  • Precision Medicine
  • Genomics and Bioinformatics

Background:

Keywords:
AsthmaBronchiectasisCOPDChronic obstructive pulmonary diseaseTreatment

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  • Chronic airway diseases, including asthma, bronchiectasis, and COPD, are complex and heterogeneous.
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