Related Experiment Video
Updated: Aug 10, 2026
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
14.7K
Multilayer flow modulator stents in aortic aneurysms: an overview based on preliminary experience
Omer Tanyeli1, Sefer Kaya2, Metin Onur-Beyaz2
1Department of Cardiovascular Surgery, Meram Faculty of Medicine, Konya.
Cirugia Y Cirujanos
|October 15, 2025
Summary
The multilayer flow modulator (MFM) approach, using the Stena MFM (S-MFM), shows promise for complex aortic aneurysms. This method successfully treated patients, shrinking aneurysms and reducing risks.
Area of Science:
- Vascular Surgery
- Medical Devices
- Aortic Aneurysm Treatment
Background:
- Complex aortic aneurysms pose high risks for traditional repair methods.
- The multilayer flow modulator (MFM) is an emerging technology for aneurysm repair.
Purpose of the Study:
- To analyze the efficacy of the multilayer flow modulator (MFM) approach.
- Evaluate outcomes in patients treated with the Stena MFM (S-MFM).
Main Methods:
- Retrospective analysis of 12 patients treated with S-MFM between July and December 2022.
- Patients were at high risk for open or endovascular aortic repair (TEVAR/FEVAR).
- 6-month follow-up outcomes were assessed.
Main Results:
- 100% technical success with no immediate interventions required.
- Successful patency of the aorta and branches confirmed by angiography.
- Complete aneurysm thrombosis observed in all patients at 6-month CT angiography.
- No significant complications like ruptures, migrations, or thrombosis occurred.
Conclusions:
- The MFM approach is a potentially attractive alternative for complex aortic aneurysms.
- MFM effectively shrinks the aneurysm sac and preserves side branch blood flow.
- This method may reduce mortality and morbidity risks associated with aneurysm repair.
Related Concept Videos
01:29Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
01:27Regulation of Stroke Volume
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
01:17Autoregulation of Blood Flow
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
01:15Aortic Regurgitation I: Introduction
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...