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Psychological and Behavioral Adjustment in Patients with Non-Traumatic Lower Limb Amputation and Prosthesis: A
Marina Maffoni1, Alessandra Casati1, Clara Tambussi1
1Psychology Unit of Montescano Institute, Istituti Clinici Scientifici Maugeri IRCCS, 27040 Montescano, Italy.
Journal of Clinical Medicine
|October 16, 2025
Summary
Psychological adaptation after lower limb amputation (LLA) is complex. Combining quantitative and qualitative methods reveals deeper insights into patients
Area of Science:
- Rehabilitation Medicine
- Psychology
- Prosthetics & Artificial Limbs
Background:
- Lower limb amputation (LLA) significantly impacts physical, psychological, and social well-being.
- Rehabilitation often prioritizes physical recovery, overlooking psychological adaptation to limb loss.
- Understanding patients' subjective experiences is crucial for holistic care.
Purpose of the Study:
- To investigate psychological and behavioral adaptation processes in patients undergoing rehabilitation post-lower limb amputation.
- To explore the lived experiences of amputees and prosthesis users.
- To assess factors influencing adaptation, including illness acceptance, body image, and social support.
Main Methods:
- Preliminary observational study using a mixed-method approach (quantitative and qualitative data triangulation).
- Inclusion of 14 inpatient amputees and 14 inpatient prosthesis users.
- Utilized validated psychometric tools (e.g., GAD-7, PHQ-9) and semi-structured interviews analyzed via Interpretive Description.
Main Results:
- Anxiety-depressive symptoms decreased with prosthesis use, improving adherence and acceptance.
- Body image was generally preserved, with some concerns about social judgment.
- Significant discrepancies noted between quantitative data (neutral) and qualitative interviews (multifaceted).
Conclusions:
- Integrating quantitative and qualitative methods provides a comprehensive understanding of adaptation post-amputation.
- Tailored psychological interventions are essential throughout the rehabilitation journey.
- Addressing psychological and subjective experiences alongside physical recovery is vital for improved patient outcomes.

