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A Double-Layer 1H/23Na Transceiver Array for Human Brain MRI at 7T.

Feiyang Lou1, Caohui Duan2, Zhiyan Quan3

  • 1The Interdisciplinary Institute of Neuroscience and Technology, School of Medcine, Zhejiang University, Hangzhou, China.

NMR in Biomedicine
|October 16, 2025
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Summary

A new double-layer 1H/23Na transceiver array enhances ultra-high-field MRI. This integrated coil improves workflow efficiency for sodium (23Na) imaging and proton (1H) structural scans at 7T.

Keywords:
RF coilsodium MRIultra‐high‐field MRI

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Area of Science:

  • Magnetic Resonance Imaging
  • Biophysics
  • Medical Imaging Technology

Background:

  • Ultra-high-field (UHF) magnetic resonance imaging (MRI) systems are increasingly adopted for clinical applications.
  • Sodium (23Na) MRI is transitioning to clinical use, but current dual-tuned coils compromise proton (1H) imaging quality.
  • This leads to workflow inefficiencies in multi-nucleus examinations.

Purpose of the Study:

  • To develop and evaluate a novel double-layer 1H/23Na transceiver array for 7T human brain MRI.
  • To address the limitations of existing coils in achieving high-resolution 1H imaging alongside 23Na imaging.
  • To improve workflow efficiency for integrated multi-nucleus MRI examinations.

Main Methods:

  • A novel eight-channel per nucleus double-layer 1H/23Na transceiver array was designed and implemented for 7T MRI.
  • The performance of the array was evaluated for both 1H and 23Na imaging modalities.
  • Quantitative comparisons of 1H signal-to-noise ratio (SNR) were made against a standard clinical 32-channel receive array.

Main Results:

  • The proposed 1H/23Na array achieved 64% of the 1H SNR compared to a standard 32-channel 1H array.
  • The integrated design successfully combined dual-nucleus imaging capabilities on a single platform.
  • Coil-switching and post-acquisition registration steps were eliminated.

Conclusions:

  • The novel double-layer transceiver array significantly streamlines clinical workflows for integrated 7T MRI.
  • This technology enhances the translational feasibility of sodium (23Na) MRI in clinical settings.
  • The improved efficiency supports advanced multi-nucleus imaging protocols.