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Mesenteric panniculitis: is it really associated with cancer? A retrospective imaging-based study
Naser Obeidat1, Mamoon Al-Omari1, Jehad Fataftah2
1Department of Diagnostic Radiology and Nuclear Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Future Science OA
|October 16, 2025
Summary
Mesenteric panniculitis (MP) is linked to specific cancers. This study found MP significantly associated with breast cancer and multiple myeloma in females, and lymphoma in males, after age adjustment.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- The association between mesenteric panniculitis (MP) and cancer remains unclear.
- Previous studies have not consistently adjusted for age when exploring this link.
Purpose of the Study:
- To investigate the association between mesenteric panniculitis and cancer.
- To determine if this association persists after adjusting for patient age.
Main Methods:
- Retrospective analysis of 8,750 abdominal CT scans from 2015-2017.
- Patients were categorized based on cancer status.
- Mesenteric panniculitis (MP) prevalence was compared between cancer and no-cancer groups.
Main Results:
- Mesenteric panniculitis (MP) was identified in 148 patients (1.7% of the total cohort).
- MP was more prevalent in patients with cancer (5.14%) compared to those without (1.36%).
- Age-adjusted analysis revealed significant associations between MP and breast cancer/multiple myeloma in females, and lymphoma in males.
Conclusions:
- Mesenteric panniculitis (MP) shows a significant association with specific malignancies.
- The study highlights a sex-specific link between MP and certain cancers, including breast cancer, multiple myeloma, and lymphoma.
