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CAM-Interacted Vision GNN for Multi-Label Medical Images
IEEE Journal of Biomedical and Health Informatics
|October 16, 2025
Summary
This study introduces a new method, CAM-interacted Vision GNN (CiV-GNN), to improve multi-label medical image classification by building category-aware graphs using Class Activation Maps (CAMs). CiV-GNN enhances object recognition and category distinctiveness in medical images.
Area of Science:
- Computer Vision
- Artificial Intelligence
- Medical Imaging Analysis
Background:
- Vision Graph Neural Networks (ViG) process images using graph-level analysis.
- ViG's reliance on appearance-level neighbors overlooks category semantics, hindering multi-label medical image learning.
- Pixel-level annotations for medical images are scarce, preventing direct construction of category-aware graphs.
Purpose of the Study:
- To propose a novel method, CAM-interacted Vision GNN (CiV-GNN), for improved multi-label medical image learning.
- To address the limitations of ViG by incorporating category semantics without manual pixel-level annotations.
- To enhance the distinctiveness of categories in medical image analysis.
Main Methods:
- Utilizing Class Activation Maps (CAMs) to localize category-specific regions without manual annotations.
- Introducing a Class-activated Patch Division (CAPD) module for category-aware graph construction guided by CAMs.
- Developing a Multi-graph Interactive Processing (MIP) module to model inter-graph relations and promote inter-category learning.
Main Results:
- CiV-GNN demonstrates strong performance in surgical tool localization and multi-label medical image classification.
- Achieved a 1.43% improvement in mAP50 and a 7.02% improvement in mAP50-95 on the m2cai16-localization dataset compared to YOLOv8.
- Effectively integrates category semantics into graph construction for enhanced image analysis.
Conclusions:
- CiV-GNN successfully overcomes the limitations of traditional ViG by incorporating category information through CAMs.
- The proposed method offers a viable solution for multi-label medical image learning, particularly when pixel-level annotations are unavailable.
- CiV-GNN shows significant potential for improving diagnostic accuracy and localization in medical imaging applications.

