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Microwave-assisted One-pot Synthesis of N-succinimidyl-4-[18F]fluorobenzoate [18F]SFB
Published on: June 28, 2011
Recent Advances and Future Trends of[18F]-Labeled PET Agents for Renal Imaging
Takahiro Higuchi1, Xinyu Chen2, Sophie C Siegmund3
1Department of Nuclear Medicine and Comprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany; Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Abstract:
Recent years have seen substantial advancements in renal positron emission tomography (PET) imaging. Targets for PET imaging include, but are not limited to, angiotensin receptors, norepinephrine transporters, and sodium-glucose cotransporters. All of those novel radiotracers inherit advantages of F18 radiochemistry, thereby allowing for higher clinical throughput or potentially increased diagnostic accuracy. The potential of such novel F18-labeled agents to yield imaging biomarkers, and their potential role for future renal molecular imaging, will be presented in the following article.
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