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Updated: May 7, 2026

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Models of Bone Metastasis
Published on: September 4, 2012
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Rapid Bone Metastasis in Hepatocellular Carcinoma: A Case Report
Laraib1, Uzma Khalid2, Ayesha Khalid3
1Medicine, Quaid-e-Azam Medical College, Bahawalpur, PAK.
Cureus
|October 17, 2025
Summary
This case study describes a rare instance of rapid bone metastasis from hepatocellular carcinoma (HCC) in a patient with hepatitis C. It emphasizes the need for vigilance regarding bone pain in HCC patients for early diagnosis and intervention.
Area of Science:
- Hepatology
- Oncology
- Radiology
Background:
- Hepatocellular carcinoma (HCC) is a prevalent liver malignancy often linked to chronic hepatitis infections.
- Extrahepatic metastases, especially to bone, typically manifest months after initial HCC diagnosis.
- This case involves a patient with a history of hepatitis C infection and liver cirrhosis.

