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Related Concept Videos

Endocrine Signaling01:45

Endocrine Signaling

67.8K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
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What is the Endocrine System?00:46

What is the Endocrine System?

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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The Endocrine System01:29

The Endocrine System

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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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An Overview of the Endocrine System01:10

An Overview of the Endocrine System

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
The endocrine system collaborates...
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Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

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Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
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Structures of the Endocrine System00:59

Structures of the Endocrine System

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The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
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Related Experiment Video

Updated: Jan 14, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
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EndoCompass project: endocrine laboratory medicine.

Annemieke C Heijboer1,2, Jacquelien J Hillebrand1,2, Brian Keevil3

  • 1Endocrine Laboratory, Department of Laboratory Medicine, Amsterdam UMC, Location University of Amsterdam and Vrije Universiteit Amsterdam, 1105 AZ Amsterdam, The Netherlands.

European Journal of Endocrinology
|October 17, 2025
PubMed
Summary

Strategic research priorities in endocrine science were identified to address hormone health challenges. The EndoCompass project highlights the need for quality assurance and innovative technologies to improve endocrine laboratory medicine and patient care.

Keywords:
LC-MS/MSanalysisbiomarkerdiversitydynamic testinghormoneimmunoassaypre-analysisstandardizationsustainability

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Area of Science:

  • Endocrinology
  • Laboratory Medicine
  • Hormone Health

Background:

  • Endocrine science is underrepresented in EU research funding despite its importance.
  • A gap exists between the societal impact of endocrine disorders and research prioritization.
  • The EndoCompass project aims to define strategic research priorities in endocrine science.

Purpose of the Study:

  • To identify and promote strategic research priorities in endocrine science.
  • To address critical hormone-related health challenges.
  • To bridge the gap in research funding and prioritization for endocrinology.

Main Methods:

  • Analysis of the EU CORDIS database (Horizon 2020).
  • Expert examination of hormone measurement challenges, analytical quality, and emerging technologies.
  • Identification of strategic research priorities for endocrine laboratory medicine.

Main Results:

  • Priorities include optimizing pre-analytical processes and standardizing endocrine tests.
  • Development of personalized reference intervals and innovative biomarker discovery are key.
  • Leveraging artificial intelligence and health economics while ensuring analytical quality is emphasized.

Conclusions:

  • Provides a roadmap for advancing endocrine laboratory medicine.
  • Supports strategic investment in quality assurance and innovative technologies.
  • Aims to enhance research reliability, clinical outcomes, and patient care for endocrine diseases.