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Thymus-derived lymphocytes: humoral and cellular reactions distinguished by hydrocortisone
Science (New York, N.Y.)
|March 10, 1972
Abstract:
Lymphocytes derived from the thymus (T cells) take part in the induction of humoral antibody and also effect cell-mediated graft-versus-host reactions. Preliminary treatment of mice with hydrocortisone caused an inhibition of T-cell function in humoral immunity, while enhancing the graft-versus-host reactivity of the same population of spleen cells. This suggests that different types of T cells participate in cellular and humoral immune reactions.